Serine protease inhibitors--N-substituted derivatives
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United States of America Patent
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Dec 14, 1999
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app pub date -
Dec 4, 1997
filing date -
Nov 21, 1994
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Expired
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Abstract
The present invention relates to oxadiazole, thiadiazole, and triazole peptoids that are inhibitors of serine protease, specifically human neutrophil elastase; which proteases are useful in treatment of adult respiratory distress syndrome, septic shock, and multiple organ failure.
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