Process for producing a hollow fiber membrane having a hydrophobic coating
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United States of America Patent
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Dec 14, 1999
Grant Date -
N/A
app pub date -
Dec 24, 1997
filing date -
Dec 25, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A process for producing a hollow fiber membrane, a hollow fiber membrane, and a dialyzer of hollow fiber membrane type is provided. The hollow fiber membrane is highly biocompatible, and the production process is quite simple and inexpensive. In the process of the invention, the hollow fiber membrane is produced in a system wherein a polymer-containing spinning solution is extruded from a tube-in-tube type orifice of a spinner in a coagulation solution to form the hollow fiber membrane. The polymer-containing spinning solution is extruded from the outer tube of the orifice to form a cylindrical filament having an inner bore and a core solution is ejected from the inner tube of the orifice into the inner bore of the filament for coagulation of the filament. The filament is directly extruded into the coagulation solution or extruded into air and then drawn to the coagulation solution. The core solution is supplemented with a hydrophobic modifier such as vitamin E and a surfactant and the resulting hollow fiber membrane contains the hydrophobic modifier on its inner surface.
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