Serine protease inhibitors-proline analogs

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United States of America Patent

PATENT NO 5998379
SERIAL NO

08985056

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Abstract

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The present invention relates to certain substituted oxadiazole, thiadiazole, and triazole peptoids that are useful as inhibitors of serine proteases, in particular human neutrophil elastase. Serine protease inhibitors of the invention are useful in the treatment of, for example, adult respiratory distress syndrome, septic shock, and myocardial ischemia-reperfusion injury.

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Patent Owner(s)

Patent OwnerAddress
CORTECH INC6840 N BROADWAY SUITE B DENVER COLORADO 80221

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gyorkos, Albert Westminster, CO 20 282
Spruce, Lyle W Chula Vista, CA 40 602

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