Perforated submucosal tissue graft constructs
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United States of America Patent
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Dec 7, 1999
Issued Date -
N/A
app pub date -
Sep 18, 1997
filing date -
Apr 5, 1996
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Abstract
A perforated unitary multi-laminar tissue graft construct and method for preparing such construct is described. The method comprises overlapping strips of submucosa tissue with other strips of submucosal tissue, compressing at least the overlapped portions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets, and perforating the resulting unitary tissue graft construct. The perforated tissue graft compositions have enhanced mechanical and remodeling properties relative to non-perforated submucosal tissue grafts.
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