Importance

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Abstract

An extracorporeal blood circulation system for treating inflammatory diseases includes a blood collection device for collecting blood from a patient suffering from an inflammatory disease, an anticoagulant mixing device for mixing an anticoagulant into the collected blood, blood transportation device for transporting the anticoagulant-containing blood at a flow rate in the range of from 20 to 200 ml/minute, a blood treating device having a blood inlet and a blood outlet and containing a platelet activating device, and a blood returning device for returning the treated blood to the patient, each being liquid-tightly connected in this order through a tubing so that when extracorporeal blood circulation is conducted using the system with respect to blood from the patient, the system is capable of providing treated blood satisfying at least one requirement selected from requirement (1) of having a .beta.-thromboglobulin concentration in the range of from 1,000 to 20,000 ng/ml and requirement (2) of having a platelet factor 4 concentration in the range of from 500 to 10,000 ng/ml. Also disclosed is an extracorporeal blood circulation method which provides treated blood in which platelets are activated to a specific degree that the above-mentioned requirement (1) and/or requirement (2) is satisfied and so as to achieve a high therapeutic effect on inflammatory diseases.

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First Claim