Methods of analysis/separation
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United States of America Patent
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-
Nov 30, 1999
Issued Date -
N/A
app pub date -
Jul 8, 1997
filing date -
Jan 21, 1993
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Particles are subjected to travelling wave field migration (TWFM) to migrate the particles over an array of microelectrodes. Altered particles are produced by treating original particles in such a way so as to alter their TWFM characteristics and the altered TWFM characteristics are employed for analysis and/or separation of the altered particles. The particles may be cells, bacteria, viruses, biomolecules or plastics microspheres. They may be altered by binding to a ligand such as a metal microparticle via a selective linking moiety such as an antibody/antigen or oligonucleic acid, or be physical or chemical treatments.
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