Nuclear matrix protein fluid assay
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United States of America Patent
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-
Nov 23, 1999
Issued Date -
N/A
app pub date -
Jun 1, 1995
filing date -
Oct 31, 1991
priority date (Note) -
In Force
status (Latency Note)
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Abstract
Disclosed are methods for determining the degree of cell death in a tissue by detecting and quantitating soluble interior nuclear matrix proteins and protein fragments in body fluids and extracellular media. The methods are is useful for monitoring the viability of cells and tissue, for evaluating the progress of a disease or its treatment, and for evaluating the cytotoxicity of unknown compounds. Also disclosed are methods for inducing the release of interior nuclear matrix proteins and protein fragments in soluble form from cells.
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Cited Art Landscape
Patent Citation Ranking
- 5 Citation Count
- G01N Class
- 2.43 % this patent is cited more than
- 26 Age