Contrast agents for MRI using a manganese compound and kojic acid
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United States of America Patent
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Nov 16, 1999
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N/A
app pub date -
Nov 3, 1997
filing date -
Aug 18, 1994
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Abstract
There is provided a contrast medium composition comprising: (a) a first contrast agent comprising a physiologically tolerable manganese compound, a physiologically tolerable reducing compound containing an .alpha.-hydroxy ketone group, or salt thereof, having a manganese concentration of at least 0.3 mM or being in a dosage unit form containing at least 300 .mu.mol manganese, together with (b) a second contrast agent. Such compositions have been found to be particularly suited to imaging of the liver.
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