Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5976822
SERIAL NO

08915414

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The ability to determine the stage or pathway of cysteine proteases in a single cell assay has long been desired as a material event in apoptosis. The present invention relates to a method and assay reagents for determining enzyme activity and relating said activity to the apoptotic pathway. In addition, the method find utility in distinguishing apoptotic activity from necrotic activity.

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Patent Owner(s)

Patent OwnerAddress
COULTER INTERNATIONAL CORPMAIL CODE 32-A02 11800 SW 147 AVENUE MIAMI FL 33196

International Classification(s)

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  • 1997 Application Filing Year
  • C12Q Class
  • 1439 Applications Filed
  • 640 Patents Issued To-Date
  • 44.48 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances1997199819992000200120022003200420052006200720082009201020112012201320140255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Del, Valle Ursino Hialeah, FL 1 58
Galiounghi, Adry Miami Lakes, FL 2 63
Garcia, Nancy Miami, FL 2 63
Landrum, Eileen Miami, FL 4 136
Lucas, Frank J Boca Raton, FL 14 304

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Patent Citation Ranking

  • 58 Citation Count
  • C12Q Class
  • 91.10 % this patent is cited more than
  • 26 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7753287423122301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +05101520253035404550556065707580

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