Process for preparing fast dispersing solid oral dosage form
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United States of America Patent
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Nov 2, 1999
Grant Date -
N/A
app pub date -
Jul 11, 1997
filing date -
Jul 11, 1997
priority date (Note) -
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Abstract
Process is provided for preparing an oral solid rapidly disintegrating freeze-dried dosage form of a pharmaceutically active substance having an unacceptable taste, wherein prior to freeze drying, a suspension of uncoated or coated coarse particles of a pharmaceutically active substance in a carrier material is cooled to reduce the viscosity and minimize release of the active substance during processing, as well as beyond the point of disintegration of the form in the mouth, to minimize bad taste from the drug.
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