Human-Th1-specific protein, gene encoding the protein, transformants, recombinant vectors, and antibodies related to the gene
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United States of America Patent
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Oct 5, 1999
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app pub date -
Jun 5, 1997
filing date -
May 19, 1997
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Abstract
An element for specifying the condition and type of immune-related diseases on the basis of the knowledge about the polarization of distribution of Th1/Th2 subsets of helper T cells. The element for specifying or correcting the polarization of the Th1/Th2 subsets is implemented by use of a recombinant vector, a transformant, a human-Th1-specific protein, and an antibody which uses the human-Th1-specific protein as an antigen. A human-Th1-specific gene is prepared and specified by a subtraction technique and is incorporated into the recombinant vector. The transformant is formed by transforming the recombinant vector. The Th1-specific protein is encoded by the gene derived from the transformant.
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