Process for producing D-amino acids with composite immobilized enzyme preparation
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United States of America Patent
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Oct 5, 1999
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N/A
app pub date -
Aug 16, 1996
filing date -
Jun 24, 1994
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Abstract
A process for the efficient production of a D-amino acid from the corresponding DL-5-substituted hydantoin by one-step reaction which comprises using a composite immobilized enzyme at a pH about neutrality, said composite immobilized enzyme being obtained by immobilizing a hydantoinase having its optimal pH within an alkaline range and a D-N-carbamyl-.alpha.-amino acid amidohydrolase having its optimal pH about neutrality in a coexisting state on an immobilizing support, simultaneously, is disclosed.
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