LH-RH antagonists having improved action
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United States of America Patent
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Aug 24, 1999
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N/A
app pub date -
May 28, 1998
filing date -
Nov 28, 1995
priority date (Note) -
Expired
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Abstract
New LH-RH antagonists are disclosed, in particular peptidomimetics and peptides modified in a side chain, their salts with pharmaceutically acceptable acids and a process for preparing these LH-RH antagonists and their salts. The disclosed peptides represent analogues of the luteinising hormone releasing hormone (LH-RH). The disclosed compounds have a high antagonistic power and are free of undesirable side effects, in particular edematogenic effects.
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