Purification of dalbaheptide antibiotics by isoelectric focusing
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United States of America Patent
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Aug 17, 1999
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Dec 18, 1997
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Jul 5, 1995
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Abstract
Method for purifying antibiotic compounds of the dalbaheptide family by means of isoelectric focusing (IEF) in a multicompartinent electrolyzer with immobiline membranes, in particular zwitterionic membranes. A further object of the invention are pure antibiotic compounds obtainable according to the present process, in particular the pure 6.sup.B -decarboxy-6.sup.B -(hydroxymethyl)-N.sup.63 -3-(dimethylamino) propyl amide derivatives of antibiotic A40926.
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