Apolipoprotein E polymorphism and treatment of Alzheimer's disease
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United States of America Patent
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Aug 10, 1999
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N/A
app pub date -
Feb 21, 1997
filing date -
Apr 27, 1994
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Abstract
The present invention relates to a method for the identification of human subjects to be responsive to cholinomimetic therapy comprising determining the absence of apolipoprotein E4 (apoE4) alleles in a biological sample of the patient where the absence of at least one apoE4 allele indicates a predisposition to respond to cholinomimetic therapy and methods of administering cholinomimetics to such identified subjects.
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