Compounds and methods for the detection and prevention of T. cruzi infection
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United States of America Patent
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Jun 29, 1999
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N/A
app pub date -
Nov 14, 1995
filing date -
Nov 14, 1995
priority date (Note) -
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Abstract
Compounds and methods are provided for diagnosing Trypanosoma cruzi infection. The disclosed compounds are polypeptides, or antibodies thereto, that contain one or more epitopes of T. cruzi antigens. The compounds are useful in a variety of immunoassays for detecting T. cruzi infection. The polypeptide compounds are further useful in vaccines and pharmaceutical compositions for inducing protective immunity against Chagas' disease in individuals exposed to T. cruzi.
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