Method of controlling the serum solubility of orally administered torasemide and composition relating thereto

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United States of America Patent

PATENT NO 5914336
SERIAL NO

09089067

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Abstract

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A method of controlling the serum solubility of orally administered torasemide is disclosed. A new crystallin modification of torasemide, called modification III which has significantly higher rates of solubilization than the known crystallin form of torasemide, modification I, is blended with amounts of modification I to produce a preselected level of torasemide in serum at a given time following administration. Compositions containing amounts of modification I and modification III, sufficient to achieve the desired serum levels of torasemide, are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
MEDA AB170 09 SOLNA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dreckmann-Behrendt, Bruno Mannheim, DE 2 14

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