Regulation of cytokine production in a hematopoietic cell

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United States of America Patent

PATENT NO 5910417
SERIAL NO

08656563

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Abstract

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A method useful for regulating cytokine production by a hematopoietic cell by regulating an MEKK/JNKK-contingent signal transduction pathway in such a cell is disclosed. Methods of identifying compounds capable of specifically regulating an MEKK/JNKK-contingent signal transduction pathway in hematopoietic cells, a kit for identifying cytokine regulators, methods to treat diseases involving cytokine production, and cells useful in such methods are also set forth.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL JEWISH CENTER FOR IMMUNOLOGY AND RESPIRATORY MEDICINE1400 JACKSON STREET DENVER CO 80206

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gelfand, Erwin W Englewood, CO 30 325
Johnson, Gary L Boulder, CO 51 657

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