6-substituted amino-4-oxa-1-azabicyclo ?3,2,0! heptan-7-one derivatives as cysteine protease inhibitors
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United States of America Patent
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May 18, 1999
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N/A
app pub date -
Apr 8, 1997
filing date -
Apr 10, 1996
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Expired
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Abstract
Novel 6-substituted amino-4-oxa-1-azabicyclo?3,2,0!heptan-7-one compounds, as well as the pharmaceutically acceptable salts thereof and diastereoisomers thereof, of formula I, ##STR1## are disclosed, which exhibit excellent cysteine protease inhibitory activity and may be used for treatment of different diseases such as muscular dystrophy, arthritis, myocardial infarction, Alzheimer's disease, bacterial infection, common cold, osteroporosis and cancer metastasis.
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