Particles based on polyamino acid(s) and capable of being used as delivery vehicles for active principle(s) and method for preparing them
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United States of America Patent
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May 18, 1999
Grant Date -
N/A
app pub date -
Mar 25, 1996
filing date -
Mar 28, 1995
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Abstract
The present invention relates to delivery vehicles which are useful for the administration of active principles (APs), preferably medicinal or nutritional active principles, in particular via the oral or parenteral route. The technical problem solved by the invention is that which consists in providing delivery vehicles composed of (nano)- or (micro)particles based on polyamino acids, and which are invert with respect to the AP (proteins), of controllable particle size, strong and inexpensive. According to the invention, the particles have an average size of less than 200 .mu.m and consist of a polyamino acid of the Leu/Glu type, in which Leu/Glu+Leu.gtoreq.3% and the M.sub.w .gtoreq.4,000 D.
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