Process for producing yttrium-90-labelled protein substrate

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United States of America Patent

PATENT NO 5902566
SERIAL NO

08630194

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Abstract

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A process for the production of yttrium-90, generated by radioactive decay of strontium-90, by means of a generator including a column containing strontium-90 adsorbed on a cation-exchange resin, wherein yttrium-90, the decay product of strontium-90, is obtained by the flow of an eluent through the resin column of the generator, an acetate buffer solution being used as the eluent. The process enables a solution to be obtained which is usable directly for labelling protein substrates, particularly monoclonal antibodies, with yttrium-90.

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Patent Owner(s)

Patent OwnerAddress
MINISTERO DELL `UNIVERSITA` E DELLA RICERCA SCIENTIFICA E TECNOLOGICAROME

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chinol, Marco Whitestone, NY 7 26
Franceschini, Rodolfo Romano Canavese, IT 3 7
Lunghi, Fabio Moncrivello, IT 3 7

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