Technique for testing and coating a microporous membrane
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United States of America Patent
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May 4, 1999
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N/A
app pub date -
Sep 22, 1997
filing date -
Sep 22, 1997
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Expired
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Abstract
The integrity of a microporous membrane within a mass transfer device such as an oxygenator is tested simultaneously with applying a biocompatible surfactant to at least the blood-contact surface of the membrane. The membrane integrity test contacts both sides of the microporous membrane with a conductive fluid to establish an electrical circuit. An electrical signal is then applied to the circuit and a measurement is taken of the test voltage across an impedance in the circuit. The value of the test voltage is used to determine the conductivity and thus the integrity of the membrane. The biocompatible surfactant is mixed with the conductive fluid used in the electrical integrity test and has an affinity for the microporous membrane material so that a durable biocompatible coating is applied to at least a portion of the microporous membrane. The biocompatible surfactant additionally reduces the drying time of the microporous membrane following the integrity test, and the surfactant may be applied to both sides of the membrane to further reduce the drying time.
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