Quinolones and their therapeutic use
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United States of America Patent
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Apr 6, 1999
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N/A
app pub date -
Aug 2, 1996
filing date -
Aug 2, 1995
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Expired
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Abstract
1-Alkyl-substituted-quinolone-3-carboxamides have therapeutic utility via inhibition of Phosphodiesterase IV esterase and/or Tumour Necrosis Factor activity. The compounds of the invention have the general formula (I): ##STR1## The compounds of the invention encompassed by formula (I) include enantiomers, diastereoisomers and mixtures, including racemic mixtures.
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