Anti-HIV agent
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United States of America Patent
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Mar 23, 1999
Grant Date -
N/A
app pub date -
Jul 23, 1996
filing date -
Jan 26, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An anti-HIV agent, an anti-HIV effect-potentiating agent and a prophylactic and remedial agent for AIDS each comprising, as an active ingredient, a vitamin B.sub.1 derivative such as thiamine disulfide, bisbentiamine, bisbutytiamine, bisibutiamine, alitiamine, fursultiamine or octotiamine, or the salt thereof. The agents according to the present invention are useful for prophylaxis of and treatment for AIDS because they have a very preferable nature that they inhibit the growth of HIV without killing cells against primarily infected cells, but exhibit both cell-killing effect and HIV-killing effect at the same time against persistent-production cells which have come to persistently produce HIV.
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