Vectors for the genetic selection of ligand binding proteins in microorganisms by means of signal transduction
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Mar 16, 1999
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Oct 22, 1997
filing date -
Jun 10, 1993
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Abstract
The invention relates to a process for the genetic selection in microorganisms of proteins which are capable of ligand binding, in which process a protein which is capable of ligand binding is presented extracytoplasmically and the signal of the ligand binding is passed on by signal transduction to the biosynthetic machinery of the micoorganism for the purpose of expressing a detectable and/or selectable function. In addition to this, the patent discloses microorganisms which are suitable for use in this process, as well as replicons and processes for their preparation.
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