Peptide compounds

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United States of America Patent

PATENT NO 5882645
SERIAL NO

08374560

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Synthetic peptides are widely used to generate antibodies. To induce high antibody response, it is known to conjugate the peptide to a carrier protein (e.g. KLH, BSA) or to incorporate it into polylysine to form a multiple antigenic peptide. Anchors may be built in which are based on fatty acids. According to the invention there is provided a novel lipidic amino acid based anchor system which can maximally enhance the antigenicity of a short synthetic peptide. These novel compounds are entirely peptide-based and may therefore be produced automatically by some step wise peptide synthesis, preferably solid phase step wise peptide synthesis. According to the invention there is also provided such a process.

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Patent Owner(s)

Patent OwnerAddress
LONDON UNIVERSITY OF SCHOOL OF PHARMACTY THE A CORP OF THE UNITED KINGDOM29/39 BRUNSWICK SQUARE LONDON WC1N

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gibbons, William Anthony Kennington, GB 1 49
Toth, Istvan Middlesex, GB 41 256

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