Method of treating patients with diabetes
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United States of America Patent
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Mar 9, 1999
Issued Date -
N/A
app pub date -
May 11, 1998
filing date -
Nov 25, 1991
priority date (Note) -
Expired
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Abstract
The present invention is directed to a method of treating a patient with diabetes by implanting an improved macrocapsule containing living islet cells in the patient. The improved macrocapsules encapsulate microcapsules containing islet cells, to make the system more biocompatible by decreasing the surface area and surface roughness of microencapsulated biological materials; increasing stability of microencapsulated islet cells; enhancing cytoprotectivity by increasing diffusion distance of encapsulated islet cells from cytotoxins secreted in vivo; providing retrievability of microencapsulated material; and providing a system of sustained release of the cellular products.
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