Bone-related cadherin-like protein and process for its production

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United States of America Patent

PATENT NO 5869638
SERIAL NO

08738349

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Abstract

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A bone-related protein named OSF-4 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein of the cadherin family. OSF-4 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-4 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.

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Patent Owner(s)

Patent OwnerAddress
HOECHST JAPAN LIMITEDTOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amann, Egon Tokyo, JP 12 71
Kawai, Shinji Fujimi, JP 84 830
Okazaki, Makoto Kawagoe, JP 47 228
Takeshita, Sunao Tokorozawa, JP 5 38
Tsujimura, Atsushi Muko, JP 3 29

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