Solid form of administration of isosorbide 5-mononitrate
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United States of America Patent
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Feb 9, 1999
Issued Date -
N/A
app pub date -
Jan 24, 1997
filing date -
Apr 27, 1993
priority date (Note) -
Expired
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Abstract
A solid form of oral administration of isosorbide 5-mononitrate with a controlled, pH-independent release of the active substance in the gastro-intestinal tract is constituted by a pellet coated with a depot layer and a release prolonging lacquer layer. The lacquer layer contains ethyl cellulose and polymethacrylate in a weight ratio from 3:1 to 3:2. The new form of administration is characterized in that it is less costly to produce.
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