Monoclonal antibodies to GP130 protein
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United States of America Patent
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Feb 2, 1999
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app pub date -
Feb 3, 1997
filing date -
Apr 28, 1992
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Abstract
Monoclonal antibodies recognizing gp130 protein and binding to the protein to inhibit IL-6 functions completely (that is to the same level as that is the absence of IL-6) when present in enough amount; a hybridoma producing the monoclonal antibody; a process for production of the monoclonal antibodies using the hybridoma; and an inhibitory agent for inhibition of physiological actions of IL-6 comprising the monoclonal antibodies.
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