Sulfonylaminopyrimidine carboxylic acid derivatives having endothelin inhibiting activity

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United States of America Patent

PATENT NO 5856484
SERIAL NO

08726712

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Abstract

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Compounds of formula I: ##STR1## are disclosed. The compounds inhibit the binding of endothelin to its receptors.

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Patent Owner(s)

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HOFFMANN-LA ROCHE INCOVERLOOK AT GREAT NOTCH 150 CLOVE ROAD 8TH FLOOR SUITE 8 LITTLE FALLS NJ 07424

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Breu, Volker D-Schliengen, DE 21 342
Burri, Kaspar Binningen, CH 18 387
Cassal, Jean-Marie Mulhouse, FR 16 241
Clozel, Martine St. Louis, FR 61 789
Hirth, Georges Huningue, FR 37 546
Loffler, Bernd-Michael Oberrimsingen, DE 7 252
Muller, Marcel Frenkendorf, CH 45 801
Neidhart, Werner Bartenheim, FR 92 714
Ramuz, Henri Birsfelden, CH 44 676

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