Inhibitors of trypsin-like enzymes

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United States of America Patent

PATENT NO 5856306
SERIAL NO

08459177

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Abstract

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Pharmaceutical compositions comprising compounds of the formula: ##STR1## in which X.dbd.H or is an N-protecting group; Y is 1-10 .alpha.-amino acids; Q1 and Q2 taken together represent the residue or a diol; R is C.sub.1-4 alkyl; and the asymmetric carbon atom marked * may have the D-or L-configuration, are useful in therapeutic methods of inhibiting thrombin.

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Patent Owner(s)

Patent OwnerAddress
THE THROMBOSIS RESEARCH INSTITUTEEMMANUEL KAYE BUILDING MANRESA ROAD LONDON SW3 6LR

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Claeson, Goran London, GB2 4 14
Metternich, Rainer Inzlingen, DE 4 62
Philipp, Manfred Hans Wilhelm Scarsdale, NY 2 4

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