Isolation and production of catalytic antibodies using phage technology
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United States of America Patent
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Jan 5, 1999
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app pub date -
Jul 14, 1994
filing date -
Jan 22, 1993
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Abstract
Disclosed and claimed are methods for producing catalytic antibodies, including human catalytic antibodies, from bacteriophage. The methods require the cloning, selection, screening, and isolation of catalytic antibodies. Also disclosed and claimed are the products themselves, the catalytic antibodies, made from the phage technology. In addition, catalytic antibodies produced from the phage technology and useful in prodrug activation are disclosed and claimed. And finally, the invention also understands the production of catalytic antibodies to phosphonates.
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