Optical and electrical methods and apparatus for molecule detection
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United States of America Patent
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Dec 8, 1998
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app pub date -
Apr 23, 1992
filing date -
Nov 19, 1991
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Abstract
A method and apparatus are disclosed for identifying molecular structures within a sample substance using a monolithic array of test sites formed on a substrate upon which the sample substance is applied. Each test site includes probes formed therein to bond with a predetermined target molecular structure or structures. A signal is applied to the test sites and certain electrical, mechanical and/or optical properties of the test sites are detected to determine which probes have bonded to an associated target molecular structure.
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