DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents
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United States of America Patent
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Dec 1, 1998
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N/A
app pub date -
May 23, 1996
filing date -
May 23, 1996
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Expired
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Abstract
The present invention relates to novel DNA alkylating agents and the prodrugs of these agents which are useful as antitumor agents and DNA labelling agents. The compounds are hydroxy dihydrobenzindole oligopeptides and prodrugs thereof wherein the monomeric constituents are derived from monocyclic or bicyclic heterocyclic aromatic residues.
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