Peptides inhibiting the oncogenic action of p21 ras
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United States of America Patent
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Nov 24, 1998
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app pub date -
Sep 21, 1995
filing date -
Sep 21, 1995
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Abstract
The present invention provides peptides and cyclized peptides which inhibit the oncogenic and/or transforming activity of the p21 ras protein, pharmaceutical compositions containing at least one of the ras-inhibiting peptides, cyclized peptides and peptidomimetics, and methods for inhibiting the ras-mediated oncogenic and/or transformation process in mammalian cells or tissues.
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