Recombinant alveolar surfactant protein
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United States of America Patent
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Nov 24, 1998
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N/A
app pub date -
Jun 7, 1995
filing date -
Dec 11, 1984
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Abstract
Recombinant materials for the production of low molecular weight hydrophobic lung surfactant proteins are disclosed and claimed. The monomeric forms of the proteins from human and canine sources have apparent molecular weights of about 5 kd and form dimers under some conditions. The availability of these recombinant materials permits production of large amounts of these proteins through recombinant techniques and permits the use of these proteins in pharmaceutical compositions in the treatment of respiratory deficiency syndromes.
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