Drug release stent coating process
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United States of America Patent
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Nov 17, 1998
Grant Date -
N/A
app pub date -
Jun 13, 1996
filing date -
Apr 19, 1995
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologically active species, possibly of controlled average particle size, to form a coating on each stent surface. The coatings are cured in situ and the coated, cured prosthesis are sterilized in a step that includes preferred pretreatment with argon gas plasma and exposure to gamma radiation electron beam, ethylene oxide, steam.
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Patent Citation Ranking
- 942 Citation Count
- B05D Class
- 98.83 % this patent is cited more than
- 27 Age