Importance

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Abstract

A serine derivative represented by the general formula (I) ##STR1## (symbols in the formula represent the following meanings; X: a sulfur atom or an oxygen atom, Y: a nitrogen atom or CH, R.sup.1 and R.sup.2 : the same or different from each other and each represents a hydrogen atom, a lower alkyl group or a protecting group for the amino group, or R.sup.1 and R.sup.2 may be combined together to form a four- to nine-membered nitrogen-containing cycloalkyl group, R.sup.3 : a hydrogen atom, a carboxyl group, a protected carboxyl group, an aralkyl group, or a lower alkyl group unsubstituted or substituted with a hydroxyl group, R.sup.4 : a hydrogen atom or a hydroxyl group, R.sup.5 : a hydrogen atom or a lower alkyl group, A: a lower alkylene group, B: 1) a saturated or unsaturated four- to ten-membered nitrogen-containing cycloalkyl group unsubstituted or substituted with a lower alkyl group or an aralkyl group or 2) a bicyclic nitrogen-containing hydrocarbon ring radical resulting from the condensation of a four- to eight-membered nitrogen-containing cycloalkyl group with a benzene ring, and . . : a single or double bond) or a pharmaceutically acceptable salt thereof, which has an anti-PCP (phencyclidine) action and is useful as a psychotropic drug.

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First Claim