DNA encoding a novel kidney ATP-dependent potassium channels
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United States of America Patent
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Nov 3, 1998
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N/A
app pub date -
Sep 9, 1996
filing date -
Sep 15, 1995
priority date (Note) -
Expired
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Abstract
The present invention comprises human DNA compositions, including cDNA clones, with full sequences, called, KIRK-2 and KIRK-3, encoding proteins that confer potassium channel activity to membranes or recipient cell lines. The DNA compositions include structural genes coding for the potassium channel proteins, expression and replication plasmids or vectors containing the structural genes and host cells expressing those genes. Methods of screening compounds for potassium channel modulating activity are also described.
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