Genes which influence pichia proteolytic activity, and uses therefor
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United States of America Patent
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Nov 3, 1998
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app pub date -
May 16, 1995
filing date -
Apr 1, 1991
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Abstract
The isolation and characterization of genes involved in proteolytic processing in species of the genus Pichia is described. The availability of such genes has enabled the generation of strains of Pichia which are deficient in proteolytic activity, which strains are useful as hosts for the expression of proteolytically sensitive recombinant products. The isolation and characterization of additional genes from species of the genus Pichia is also described, as well as uses therefore.
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