Method for clinical examination based on the structures of immunoglobin G-linked oligosaccharides
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United States of America Patent
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Nov 3, 1998
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N/A
app pub date -
Jul 12, 1995
filing date -
Jul 14, 1994
priority date (Note) -
Expired
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Abstract
The present invention relates to a novel clinical examination method which comprises analyzing the alteration in the amount of a specific component in oligosaccharides of immunogloblin G. Human diseases such as liver diseases, malignant hypertension, immunogloblin A-nephropathy, pediatric disorders, etc., are examined in terms of the alteration in bisecting N-acetylglucosamine-containing oligosaccharides in immunogloblin G from collected humor. The present invention provides highly accurate information in a manner applicable to practical operation for examination of liver diseases, allergic diseases, malignant hypertension, immunogloblin A nephropathy, pediatric disorders, as well as aging-dependent variations and the therapeutic effect of interferon.
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