Herpes simplex virus amplicon mini-vector gene transfer system

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United States of America Patent

PATENT NO 5830727
SERIAL NO

08578500

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Abstract

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A novel HSV mini viral vector is disclosed. The vector comprises HSV and EBV genes which allow it to remain in episomal state, to have very high transfection and infection, and to tolerate up to 140 kb of foreign DNA. Techniques and genetic constructs for producing the vectors, for constructing the vectors and transfection and infection to recipient cells are disclosed.

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Patent Owner(s)

Patent OwnerAddress
HUMAN GENE THERAPY RESEARCH INSTITUTE1415 WOODLAND AVENUE IOWA METHODIST MEDICAL CENTER DES MOINES IA 50309

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Link, Jr Charles J Des Moines, IA 11 98
Wang, Suming Des Moines, IA 8 73

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