Substituted pyrrolidin-3-yl-alkyl-piperidines
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United States of America Patent
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Oct 20, 1998
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N/A
app pub date -
Feb 11, 1997
filing date -
May 6, 1993
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Expired
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Abstract
The present invention relates to substituted pyrrolidinyl-3-yl-alkyl-piperidines, their stereoisomers, and pharmaceutically acceptable salts thereof and processes for preparation of the same. The compounds of the present invention are useful in their pharmacological activities such as tachykinin antagonism, especially substance P and neurokinin A antagonism, and the like. Compounds having the property of tachykinin antagonism are indicated for conditions associated with neurogenic inflammation and other diseases described herein.
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