Anti-human soluble fibrin antibody, hybridoma, and immunoassaying method
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United States of America Patent
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Oct 13, 1998
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app pub date -
Sep 22, 1995
filing date -
Nov 2, 1993
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Abstract
A monoclonal antibody that reacts with a human soluble fibrin but not with a human fibrinogen; a hybridoma that secretes the above antibody; and a method of assaying a human soluble fibrin with the above antibody. It is possible to determine the amount of soluble fibrin in the plasma of a patient specifically, readily and rapidly by agglutination and EIA without being affected by plasma fibrinogen, plasmin-degradation product of fibrinogen, fibrin fragment, and plasmin-degradation product of stabilized fibrin even without pretreating the plasma sample.
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