Recombinant kat enzyme from rat

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United States of America Patent

PATENT NO 5817496
SERIAL NO

08271667

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Abstract

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Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of: (a) an isolated DNA sequence which encodes rat KAT; (b) an isolated DNA sequence which hybridizes to the isolated DNA sequence of (a) above and which encodes a KAT enzyme; and (c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme. Also disclosed are vectors and host cells containing the same; oligonucleotide probes for identifying kynurenine aminotransferase; and isolated and purified kynurenine aminotransferase.

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Patent Owner(s)

Patent OwnerAddress
PHARMACIA & UPJOHN S P AVIA ROBERT KOCH 1/2 MILAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benatti, Luca Milan, IT 18 61
Breton, Jerome Milan, IT 3 15
Mosca, Monica Milan, IT 3 13
Okuno, Etsuo Wakayama, JP 2 13
Schwarcz, Robert Baltimore, MD 22 78
Speciale, Carmela Milan, IT 14 51

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