Method of making liposomes with improved stability during drying

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United States of America Patent

PATENT NO 5817334
SERIAL NO

08469156

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Abstract

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A composition and method are provided for the making of cholesterol containing phospholipid liposomes such that when dried and then reconstituted, the liposomes retain their structure and size distribution as well as substantially all of the material that was originally encapsulated, and they behave biologically in a normal fashion. The cryoprotective agents are used in the aqueous medium to hydrate the phospholipid(s) and are a combination of at least one sugar and at least one protein, polypeptide, and/or oligopeptide.

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Patent Owner(s)

Patent OwnerAddress
NEXSTAR PHARMACEUTICALS INC650 CLIFFSIDE DRIVE SAN DIMAS CA 91773 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujii, Gary Torrance, CA 16 220
Schmidt, Paul G San Marino, CA 11 710

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