Preventive and remedy for type 1 allergic diseases
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United States of America Patent
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Sep 29, 1998
Grant Date -
N/A
app pub date -
Jun 6, 1997
filing date -
Oct 17, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A pharmaceutical composition for prophylaxis or treatment of Type I allergic diseases which comprises as an active ingredient an anilide compound represented by the general formula (I) ##STR1## ?wherein R.sub.1 is a trifluoromethyl group, a halogen atom or a cyano group, R.sub.2 is a hydrogen atom or a straight or branched C.sub.1 -C.sub.4 alkyl group and R.sub.3 is a group of the formula (II) or (III) ##STR2## (wherein R.sub.4 is a straight or branched C.sub.1 -C.sub.4 alkyl group, a straight or branched C.sub.2 -C.sub.6 alkenyl group, a straight or branched C.sub.2 -C.sub.6 alkynyl group or a C.sub.2 -C.sub.6 cycloalkyl group) or a stereoisomer thereof or a physiologically acceptable salt thereof. The present composition remarkably inhibits the production of IgE, which is the direct cause of Type I allergic diseases, and it can radically prevent or cure Type I allergic diseases.
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