Cyclic CS-1 peptidomimetics, compositions and methods of using same
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United States of America Patent
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Sep 22, 1998
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N/A
app pub date -
Jun 7, 1995
filing date -
Aug 25, 1994
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Expired
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Abstract
The present invention contemplates a cyclic peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated cyclic peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory cyclic peptide are also disclosed.
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