Methods for the activation of proliferation of animal cells
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United States of America Patent
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Sep 22, 1998
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N/A
app pub date -
Feb 7, 1995
filing date -
Feb 8, 1994
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Expired
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Abstract
Cell cultures are described which proliferate in a serum- and protein-free environment and which are characterized by the circumstance that the concentration of at least one cell-cycle-regulatory protein is increased during at least one period of the cell-cycle. Methods for the production of such cell cultures are presented. With these methods cell lines can be transferred to serum- and protein-free growth that are already in use in a production process which, prior to the use of these methods, requires serum or proteins added to the basal medium.
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